Autologous micrografting, designed for the point of care.
A tissue-specific cartilage sample, mechanically prepared through Rigenera® technology and collected as an autologous micrograft suspension within one professional pathway.
Professional orientation only. The current protocol, instructions, training and clinical judgement remain authoritative.
Professional system
Tissue in. AMT® solution out.
No laboratory expansion or enzymatic digestion in the documented pathway.
The science behind AMT®
The mechanism is the product story.
Mytocel MSK® uses gentle mechanical disaggregation to prepare micrografts from auricular cartilage. The supplied material describes a heterogeneous, tissue-specific suspension containing cartilage-derived cellular and extracellular-matrix components.
Autologous micrografting technology
From a tissue-specific sample to a point-of-care suspension.
- 01
Cartilage origin
A small sample is collected from the patient’s auricular cartilage according to the professional protocol.
- 02
Tissue-specific components
The sample retains cartilage-derived cells and extracellular-matrix components from the donor tissue.
- 03
Mechanical disaggregation
Rigenera technology mechanically prepares micrografts with a documented 80 μm cut-off without laboratory expansion.
- 04
Point-of-care suspension
The resulting autologous micrograft suspension is collected for administration within the same clinical pathway.
This visual summary is an orientation to the supplied professional material. It does not replace the protocol or establish comparative clinical effectiveness.
Open the science and HCP brochurePatented Rigenera® technology devices
A controlled mechanical-processing system.
The system
Two core devices. One documented workflow.
Rigeneracons® RS
Sterile, single-use device designed to mechanically disaggregate the cartilage sample while preserving micrograft viability.
N4SA Machine 2.0
Electromechanical unit that provides the calibrated rotational impulse used in the documented processing stage.
Clinical setup
A sterile field, defined consumables and appropriate professional training complete the point-of-care setup.
The professional protocol
Four stages. One point-of-care pathway.
Technique, equipment, patient selection and sterile procedure details belong in the controlled protocol and formal product training. This sequence shows the relationship between the stages.
- 01
Preparation & anaesthesia
Prepare the auricular donor area, establish a sterile field and administer local anaesthesia according to the professional protocol.
- 02
Cartilage extraction
Obtain three small samples from the auricular cartilage using the documented punch technique.
- 03
Disaggregation & collection
Process the sample in Rigeneracons® RS and collect the prepared autologous micrograft suspension.
- 04
Infiltration
Administer the suspension to the target joint within the same point-of-care clinical pathway.
Procedure film · 4 min 50 sec
See preparation, sampling, processing and collection in sequence.
Open the quick guidePublished evidence
09
Publications in the supplied scientific booklet
Make the evidence visible before asking someone to download it.
The supplied library spans biological rationale, pre-clinical work and clinical reports. The clinical records are small and largely uncontrolled, so study design and limitations remain part of the presentation.
Featured record · Study 05
Three-year follow-up in knee chondropathy.
The Marcarelli case series followed eight patients and reported clinical scores alongside standardised MRI measurements. The long follow-up is useful context; the very small uncontrolled design does not support broad comparative claims.
Complete evidence index
Nine publications, in their supplied context.
Open each publication at its position in the 116-page scientific booklet. Evidence type is stated before the title so pre-clinical work and clinical reports are not conflated.
Professional resource library
Everything a clinic needs to review, in one place.
Use the current protocol and controlled documentation for operation and safety. The supporting material helps teams assess the science, setup and onboarding pathway.
Studies at a glance
Five supplied visual evidence summaries.
These concise summaries sit alongside—not instead of—the complete nine-publication scientific booklet.
Questions before adoption
The practical questions a clinical team should ask.
Open the complete HCP FAQWhat is Mytocel MSK?+
Mytocel MSK is a point-of-care autologous micrografting procedure. A small sample of auricular cartilage is mechanically disaggregated using Rigenera® technology to create a tissue-specific micrograft suspension for administration to the target joint.
What is the AMT® solution?+
AMT® refers to the autologous micrograft suspension produced by the documented mechanical-disaggregation process. The supplied professional material describes cartilage-derived cells and extracellular-matrix components within micrografts prepared using an 80 μm cut-off.
Which patients are covered by the supplied professional material?+
The professional protocol focuses on mild to moderate osteoarthritis up to grade III. Patient selection, contraindications and any use outside that scope must follow the current controlled documentation and clinical judgement.
What does a clinic need in addition to the Mytocel components?+
The HCP material lists sterile drapes and gloves, antiseptic, local anaesthetic, saline, syringes, needles, a 2.5 mm dermal punch, sterile forceps and dressing materials. Use the current quick guide and protocol for the complete list.
What evidence is available?+
The supplied scientific booklet contains nine publications spanning scientific rationale, pre-clinical work and small clinical cohorts. The clinical reports provide useful signals but are not comparative proof; design, sample size and limitations should remain visible when interpreting outcomes.
Buying and supply questions
How to buy Mytocel MSK through Actomed
Answers for healthcare professionals and clinics comparing suppliers, planning training or preparing to introduce Mytocel MSK in the UK.
Where can healthcare professionals buy Mytocel MSK in the UK?
Healthcare professionals, clinics and clinic groups can contact Actomed for Mytocel MSK product and supply information in the UK. Start with your professional role, organisation, service region and intended clinic pathway.
How does a clinic order Mytocel MSK?
Use the Actomed supply enquiry route to discuss the product system, disposable components, clinical setting and support required. Actomed can then confirm the appropriate account, training and fulfilment steps.
What equipment is needed to introduce Mytocel MSK?
The professional protocol describes the N4SA device, Rigeneracons RS and the sterile equipment and consumables required for the pathway. Clinic requirements should be reviewed against the current controlled documentation before first use.
Is Mytocel MSK available through consumer ecommerce?
Actomed uses a professional enquiry process rather than open consumer ecommerce. Supply is discussed with healthcare professionals and clinics in the context of the product system, setting and onboarding needs.
Can I request Mytocel MSK training for my clinic?
Select training or clinic onboarding on the Actomed enquiry form. Include your professional role, clinic, team and current orthobiologic experience so the relevant training route can be discussed.
Professional enquiries
Assess Mytocel MSK for your clinic
Ask about the professional pack, UK product supply, training and the practical requirements for first use.